1. Introduction about the Lab

The Jin Lab integrates multidisciplinary approaches to interrogate the molecular underpinnings of metastatic cancer and strives to find therapeutic targets for tackling this deadly disease. We are establishing a next-generation cancer research framework that combines high-throughput technologies and in vivo models that are more physiologically recapitulative of patient settings, unleashing their power for large-scale metastasis mechanism exploration. We incorporate perturbational, single cell, and spatial genomics tools to chart tumor evolution and therapeutic response in space and time, identifying unmarked oncotargets with selectivity and therapeutic index. We utilize machine learning and bioinformatic approaches for biomarker and resistance mechanism discovery. Through these efforts we aim to make impactful findings that are translatable to precision medicine for metastatic cancer. For details, please visit the following:

Dr. Jin’s webpage

JinLab website

2. Job Openings

We are looking for exceptional candidates to join the research effort to delineate in vivo cancer dependencies and discover novel therapeutic targets. The candidates will drive the development of novel functional genomics approaches including high-throughput in vivo assays, CRISPR gene perturbation/control tools, and cell phenotyping technologies. He/she will combine these approaches with computational biology to conduct large-scale cancer research and develop mechanistic insights. The candidates are expected to lead the research and work independently on a daily basis, and will receive solid scientific training mentored by the principal investigator of the group. He/she will have the opportunity to widen their vision about cancer research through interacting with multiple top laboratories around the world. Westlake University provides a vibrant research environment with close links to top academic institutions across China and provides the potential for individuals’contributions to be used and recognized worldwide.

(1) Positions for Research Assistant Professor (1)

Job Responsibilities:

1) Establish data analysis methodologies and framework, including single cell sequencing, next-generation sequencing, genomics data, high-throughput screening data, high-content imaging data and etc.

2) Develop custom analysis pipeline for projects, dataset compiling and sharing, data I/O interface design.

3) Assist PI in lab management and supervision of lab trainees.

4) Lead independent research and grant application.

Requirements:

1) PhD degrees in Computational Biology, Bioinformatics or related fields, postdoc experience desired.

2) Strong expertise in programming, including but not limited to Python, R, or Metlab languages, experience in machine learning and in NGS, genomics, or imaging data analysis desired.

3) Proficient in scientific writing and English communication. 

4) Strong learning skills, organized and efficient, great attention to detail. 

5) Ability to handle a variety of tasks in a fast-paced environment, strong time-management skills.

6) Highly motivated, open-minded, collaborative, attention to team ethics.

(2) Positions for Research Assistant Professor (1)

Job Responsibilities:

1) Lead the Metastasis Map project, combining barcoding, single cell and spatial genomics approaches to create a panorama of pan-cancer metastasis map.

2) Involved in the development of functional genomics approaches to cancer target discovery

3) Assist PI in lab management and supervision of lab trainees.

4) Lead independent research and grant application.

Requirements:

1) PhD degrees in the following fields, postdoc experience desired:

• Cancer Biology / Cell Biology: cancer research, primary cell culture, stem cell, organoid, cell signaling.

• Molecular Biology / Chemical Biology: gene editing, viral vector, screening library construction, high-throughput screening, DNA/RNA/protein biochemistry characterization.

• Animal surgery and working experience, pharmacokinetic/pharmacodynamic (PK/PD) modeling.

2) Strong scientific standing and background knowledge, strong publication record and diverse research skills.

3) Proficient in scientific writing and English communication. 

4) Strong learning skills, organized and efficient, great attention to detail. 

5) Ability to handle a variety of tasks in a fast-paced environment, strong time-management skills.

6) Highly motivated, open-minded, collaborative, attention to team ethics.

(3) Positions for Research Assistants (2)

Job Responsibilities:

1) Take responsibility in the daily lab operation, lab supply and safety management. 

2) Assist PI in lab management. 

3) Learn the core research techniques developed from the laboratory, conduct experiments, and participate in projects.

4) Assist other lab members and fulfill assigned tasks. 

5) Lab protocol and notebook summary and organization.

Requirements

1) Bachelor of Science degrees or above, Biological Science related majors are desired.

2) Animal working experience, or experience in tissue culture, cell biology, fluorescence microscopy, flow cytometry, biochemistry, or molecular biology is preferred.

3) Proficient in English communication.

4) Strong learning skills, organized and efficient, great attention to detail.

5) Ability to handle a variety of tasks in a fast-paced environment, strong time-management skills. 

6) Highly motivated, open-minded, collaborative, attention to team ethics.

3. Compensation and Benefits

Westlake Laboratory offers a competitive compensation package commensurate with the selected candidate’s qualifications and experience.

4. How to apply

To apply, please send the following documents in English as PDF files to jinxin@westlake.edu.cn, and indicate Name + Position in the email subject.

(1) CV

(2) Cover letter and other accompanying materials that can make yourself stand out

(3) Degree certificates

(4) Three reference letters, addressed directly to jinxin@westlake.edu.cn