Introduction of The Lab/ Research Field

    The Jin Lab integrates multidisciplinary approaches to interrogate the molecular underpinnings of metastatic cancer and strives to find therapeutic targets for tackling this deadly disease. We are establishing a next-generation cancer research framework that combines high-throughput technologies and in vivo models that are more physiologically recapitulative of patient settings, unleashing their power for large-scale metastasis mechanism exploration. We incorporate perturbational, single cell, and spatial genomics tools to chart tumor evolution and therapeutic response in space and time, identifying unmarked oncotargets with selectivity and therapeutic index. We utilize machine learning and bioinformatic approaches for biomarker and resistance mechanism discovery. Through these efforts we aim to make impactful findings that are translatable to precision medicine for metastatic cancer. For details, please visit:

Dr. Jin’s webpage

The JinLab website

Job Description

Position: Postdoctoral Fellow (1-2)

The Jin Lab at Westlake University is looking for exceptional candidates to join the research effort to delineate in vivo cancer dependencies and discover novel therapeutic targets. The candidates will drive the development of novel functional genomics approaches including high-throughput in vivo assays, CRISPR gene perturbation/control tools, and cell phenotyping technologies. He/she will combine these approaches with computational biology to conduct large-scale cancer research and develop mechanistic insights. The candidates are expected to lead the research and work independently on a daily basis, and will receive solid scientific training mentored by the principal investigator of the group. He/she will have the opportunity to widen their vision about cancer research through interacting with multiple top laboratories around the world. Westlake University provides a vibrant research environment with close links to top academic institutions across China and provides the potential for individuals’ contributions to be used and recognized worldwide.

Requirements:

The projects adopt interdisciplinary approaches and are suitable for candidates from diverse experimental and computational biology disciplines. Candidates majored in medicine, computer science, engineering, chemistry, mathematics, physics, and with a strong interest in cancer research are also encouraged to apply. Relevant scientific backgrounds include but are not limited to:

1) Cancer Biology / Cell Biology: cancer research, primary cell culture, stem cell, organoid, cell signaling;

2) Molecular Biology / Chemical Biology: gene editing, viral vector, screening library construction, high-throughput screening, DNA/RNA/protein biochemistry characterization;

3) Bioinformatics / Computational Biology: single cell sequencing, in situ sequencing, next-gen sequencing, genomics, imaging analysis, machine learning;

4) Bioengineering: microfluidics, microscopy, bio-scaffold, 3D printing;

5) Animal surgery and working experience, pharmacokinetic/pharmacodynamic (PK/PD) modeling.

Other requirements:

1) Have obtained or about to obtain a Ph.D. degree, aged under 35;

2) Strong scientific standing and background knowledge, strong publication record and diverse research skills;

3) Proficient scientific writing skills and English communication skills;

4) Strong learning skills, organized and efficient, great attention to detail;

5) Ability to handle a variety of tasks in a fast-paced environment, strong time-management skills;

6) Highly motivated, open-minded, collaborative, attention to team ethics.                                                                                                  Compensation and Benefits

The research team offers a competitive compensation package commensurate with the selected candidate’s qualifications and experience. Applications for relevant projects and programs will be encouraged and supported. For post-doc(s) who selected for China Postdoctoral Science Foundation or Advanced Programs of Zhejiang Province will be entitled to receive the same amount funds from the Hangzhou government. For post-doc(s) who full-time work in Hangzhou after completing their post-doc research will be eligible for applying allowance of 400,000RMB from the Hangzhou government.

How to Apply

To apply, please send the following documents in English as PDF files to jinxin@westlake.edu.cn, and indicate the Post-doc application in the email subject.

1) CV;

2) Cover letter and other accompanying materials that can make yourself stand out;

3) Doctoral degree and other degree certificates;

4) Three reference letters, addressed directly to jinxin@westlake.edu.cn (One of them is from the doctoral supervisor)