Introduction of The Lab

Pei Duanqing's group in the School of Life Sciences at Westlake University is dedicated to the study of cell fate regulation mechanisms, combining structural biology, molecular biology, cell biology, bioinformatics and systems biology to explore the regulatory mechanisms in the process of typical cell fate changes in various models of plants and animals, and the relevant platforms have been built. The group welcomes young scholars with strong scientific interests to join our dynamic research team. The current research directions include but are not limited to:

Multi-dimensional analysis of cell fate regulation mechanism

- "Structural elucidation of key protein machinery in cell fate determination process"

- "Study of regulatory mechanisms of cardiac development and disease repair using single cell technology"

- "Mechanisms of cell fate regulation during early embryonic development"

- "Exploring the mechanism of liquid-liquid phase separation in cell fate regulation"

- "Quantitative model construction of cell fate regulation"

Diversified establishment of cell fate regulation system

- "Large Animal Stem Cells and Organ Regeneration"

- "The establishment of plant stem cell culture system and the molecular mechanism of its totipotency"

- "Reprogramming of human-derived urothelial cells and establishment of downstream organoid"

- "Developmental regulation of germ cells and related applications"

Professor Duanqing Pei is a world-renowned expert in stem cell research and regenerative medicine. He has made many significant discoveries in the fields of stem cell fate regulation and cell reprogramming, including: the mechanism of the role of EMT-MET in reprogramming (awarded the second prize of the National Natural Science Award in 2018), the mechanism of the role of Vc in somatic cell reprogramming (awarded the second prize of the National Natural Science Award in 2013), and proposed a binary transition mechanism of cell fate regulation chromatin on/off with results being published in leading international journals such as Cell Stem Cell, Nature Genetics, Nature Cell Biology, Nature Communications, Cell Reports, etc.

Job Description

Position: Postdoctoral Fellow- Bioinformatics

Requirements:

(1) Have obtained or will obtain a PhD in bioinformatics, computational biology, physics, statistics, mathematics or other related fields;

(2) Familiar with bioinformatics analysis methods, strong programming skills (Python/R/Shell) with rapid and good understanding and hands-on ability for new technologies, methods and knowledge;

(3) At least one first author paper published in Bioinformatics, PLoS Computational Biology or above;

Position: Postdoctoral Fellow- Large Animal Stem Cell and Organ Regeneration Research

Requirements:

(1) Have obtained or will obtain a PhD in cell biology, developmental biology, molecular biology, immunology or other related fields;

(2) Excellent experimental skills in cell biology, molecular biology and biochemistry, with an open mind for new technologies, methods and novelties;

(3) Experience in human or large animal stem cell pluripotency, organ regeneration, early embryonic development, chimera production, humanized animal models, compound screening or other related contents;

(4) Experience in porcine somatic cell cloning, gene editing, and stem cell culture is preferred.

Position: Postdoctoral Fellow- Other Research Directions

Requirements:

(1) Have obtained or will obtain a PhD degree in plant science, cell biology, developmental biology, molecular biology, immunology, bioinformatics, and other related fields;

(2) Familiar with the experimental methods and means of cell biology, molecular biology and biochemistry, with fast and good understanding and hands-on ability for new technologies, new methods and new things; bioinformatics direction needs to be familiar with bioinformatics analysis methods and means, with strong programming basis, with good understanding and hands-on ability for new technologies, new methods and new things;

(3) Experience in humanized antibody design, preparation and screening is preferred.

Other requirements for all postdoctoral fellows:

(1) ≤ 35 years old;

(2) Strong work ethic and good personality;

(3) Excellent English writing and verbal communication skills.

Compensation and Benefits

1. The research team offers a competitive and negotiable compensation package commensurate with the candidate’s qualifications and experience. Applications for relevant projects and programs will be encouraged and supported.

2. The university assists with enrolling children in child care and school.

3. The university boasts comprehensive postdoctoral training, with programs including the Westlake University Outstanding Postdoctoral Fellows and Westlake Postdoctoral Fellowship for Women.

Funding

1. Postdocs receive a living allowance and research funding from the Hangzhou municipal government.

2. Recipients of funding from the China Postdoctoral Science Foundation or the Zhejiang Province Selected Funding for Postdoctoral Research Projects are entitled to supplementary funding of the same amount from the Hangzhou municipal government.

3. Postdocs who work full-time in Hangzhou after completing their postdoctoral research qualify for an allowance of 400,000 RMB from the Hangzhou municipal government.

4. Eligible new university graduates holding a doctoral degree or equivalent who work full time in Hangzhou (including those who studied abroad and returned to China within 5 years of graduation as well as foreign talent) can apply to the Hangzhou municipal government for a living allowance of 100,000 RMB.

5. Postdocs recognized as high-level talent in Hangzhou enjoy corresponding preferential policies.

How to Apply

To apply, please send the following documents in English as one PDF file to Peilabrecruitment@westlake.edu.cn and indicate the Post-doc application in the email subject.

(1) CV;

(2) 2 reference letters (One of them is from the doctoral supervisor);

(3) Doctoral Degree Certificate.