(*First and co-first author; # corresponding)

1. Qi Chen, Peiguo Yang^#. Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity. Cell Rep. 2025; 44(6):115766.

2. Zhiying Yao^#, Yi Liu, Peiguo Yang^#. Protocol for multi-component reconstitution of stress granules in vitro. STAR Protoc. 2025; 6(1):103666.

3. Zhiying Yao, Ziqiu Wang, Peiguo Yang^#. The G3BP1 RNP complex at focal adhesion tunes cell migration. Trends Cell Biol. 2025; 35(3):180-182.

4. Qi Chen, Xiaoxin Chen, Peiguo Yang^#. Proteasomes safeguard the plant stress granule homeostasis. Mol Cell. 2024; 84(17): 3169-3170.

5. Zhiying Yao, Yi Liu, Qi Chen, Xiaoxin Chen, Zhenshuo Zhu, Sha Song, Xianjue Ma, Peiguo Yang^#. The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network. Cell Rep. 2024; 43(8):114617.

6. Yi Liu, Peiguo Yang^#. eIF4G as a switch for heat shock mRNA translation. Mol Cell. 2024; 84(9):1633-1634.

7. Ke Ruan^#, Yi Lin#, Peiguo Yang^#, Wen Zhou^#. Condensation matters. Nat Chem Biol. 2023;19(10):1180-1182.

8. Zhenshuo Zhu, Peiguo Yang^#. RNA repeats stall translation. Nat Chem Biol. 2023;19(11):1299-1300.

9. Yi Liu, Zhiying Yao, Guiwei Lian, Peiguo Yang^#. Biomolecular phase separation in stress granule assembly and virus infection. Acta Biochim Biophys Sin (Shanghai). 2023;55(7):1099-1118.

10. Peiguo Yang*, Cécile Mathieu*, Regina M. Kolaitis, Peipei Zhang, James Messing, Ugur Yurtsever, Zemin Yang, Jinjun Wu, Yuxin Li, Qingfei Pan, Jiyang Yu, Erik W. Martin, Tanja Mittag, Hong Joo Kim, J. Paul Taylor. G3BP1 is a tunable switch that triggers phase separation to assemble stress granules. Cell 2020; 181: 325-345.

11. Peiguo Yang, Hong Zhang. You are what you eat: multifaceted functions of autophagy during C. elegans development. Cell Res 2014; 24: 80-91.

12. Sihui Li*, Peiguo Yang*, E Tian, Hong Zhang. Arginine Methylation Modulates Autophagic Degradation of PGL Granules in C. elegans. Mol. Cell 2013; 52: 421-33.

13. Peiguo Yang, Hong Zhang. The coiled-coil domain protein EPG-8 plays an essential role in the autophagy pathway in C. elegans. Autophagy 2011; 7: 159-65.

14. Yinyan Sun*, Peiguo Yang*, Yuxia Zhang*, Xin Bao, Jun Li, Wenru Hou, Xiangyu Yao, Jinghua Han, Hong Zhang. A genome-wide RNAi screen identifies genes regulating the formation of P bodies in C. elegans and their functions in NMD and RNAi. Protein Cell 2011; 2:918-39.

15. Yuxia Zhang*, Libo Yan*, Zhi Zhou*, Peiguo Yang*, E Tian, Kai Zhang, Yu Zhao, Zhipeng Li, Bing Song, Jinghua Han, Long Miao, Hong Zhang. SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans. Cell 2009; 136:308-21.

16. Yin Li, Jie Fang, Yuqi Ding, Xilong Zhang, Ying Liu, Wanting Qiu, He Xu, Yunzhe Kang, Jiayu Chen, Yanyan Gao, Yan G Zhao, Peiguo Yang, Bo Wang, Wenmin Tian, Yang Chen, Wenjian Bi, Peipei Zhang. β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1. Nat Commun. 2025;16(1):5227.

17. Pan Geng, Changxuan Li, Xuebo Quan, Jiaxuan Peng, Zhiying Yao, Yunhe Wang, Ming Yang, Yanning Wang, Yunfan Jin, Yan Xiong, Hongtao Liu, Yijun Qi, Peiguo Yang, Kai Huang, Xiaofeng Fang. A thermosensor FUST1 primes heat-induced stress granule formation via biomolecular condensation in Arabidopsis. Cell Res. 2025; 35(7):483-496.

18. Jinglei Nie, Xinyi Zhang, Zhijuan Hu, Wei Wang, Martin A. Schroer MA, Jie Ren, Dmitri Svergun, Anyang Chen, Peiguo Yang, Anping Zeng. A globular protein exhibits rare phase behavior and forms chemically regulated orthogonal condensates in cells. Nat Commun. 2025; 16(1):2449.

19. Zehua Shang, Sitao Zhang, Jinrui Wang, Lili Zhou, Xinyue Zhang, Daniel D Billadeau, Peiguo Yang, Lingqiang Zhang, Fangfang Zhou, Peng Bai, Da Jia. TRIM25 predominately associates with anti-viral stress granules. Nat Commun. 2024;15(1):4127.

20. Ting Qiu, Yichao Kong, Guifeng Wei, Kai Sun, Ruijie Wang, Yang Wang, Yiji Chen, Wenxin Wang, Yun Zhang, Caihong Jiang, Peiguo Yang, Tian Xie, Xiabin Chen. CCDC6-RET fusion protein regulates Ras/MAPK signaling through the fusion- GRB2-SHC1 signal niche. Proc Natl Acad Sci U S A. 2024;121(23):e2322359121.

21. Qinqin Cui, Hongyun Bi, Zhanyun Lv, Qigui Wu, Jianfeng Hua, Bokai Gu, Chanjuan Huo, Mingmin Tang, Yanqin Chen, Chongjiu Chen, Sihan Chen, Xinrui Zhang, Zhangrui Wu, Zhengkai Lao, Nengyin Sheng, Chengyong Shen, Yongdeng Zhang, Zhi-YingWu, Zhigang Jin, Peiguo Yang, Huaqing Liu, Jinsong Li, Ge Bai. Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules. Cell 2023;186(4):803-820.e25.

22. Brian D Freibaum, James Messing, Peiguo Yang, Hong Joo Kim, J. Paul Taylor. High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate. J Cell Biol 2021;220(3):e202009079.

23. Anna K. Lee, Jonathon Klein, Klementina Fon Tacer, Tessa Lord, Melissa J. Oatley, Jon M. Oatley, Shaina N. Porter, Shondra M. Pruett-Miller, Elena B. Tikhonova, Andrey L. Karamyshev, Yong-Dong Wang, Peiguo Yang, Ane Korff, Hong Joo Kim, J. Paul Taylor, and Patrick Ryan Potts. Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance. Mol. Cell 2020; 79: 645-59.

24. Cristina Batlle, Peiguo Yang, Maura Coughlin, James Messing, Mireia Pesarrodona, Elzbieta Szulc, Xavier Salvatella, Hong Joo Kim, J. Paul Taylor and Salvador Ventura. hnRNPDL phase separation is regulated by alternative splicing and disease-causing mutations accelerate its aggregation. Cell reports 2020; 30:1117–1128.

25. Peipei Zhang, Baochang Fan, Peiguo Yang, Jamshid Temirov, James Messing, Hong Joo Kim, J Paul Taylor. Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology. eLife 2019;8:e39578

26. Yubing Liu, Wei Zou, Peiguo Yang, Li Wang, Yan Ma, Hong Zhang, Xiaochen Wang. Autophagy-dependent ribosomal RNA degradation is essential for maintaining nucleotide homeostasis during C. elegans development. eLife 2018;7:e36588

27. Ke Zhang, Gavin Daigle, Kathleen M. Cunningham, Alyssa N. Coyne, Kai Ruan, Jonathan C. Grima, Kelly E. Bowen, Harsh Wadhwa, Peiguo Yang, Frank Rigo, J. Paul Taylor, Aaron D. Gitler, Jeffrey D. Rothstein and Thomas E. Lloyd. Stress Granule Assembly Disrupts Nucleocytoplasmic Transport. Cell 2018; 173: 958-971.

28. Tommaso Poggioli*, Ana Vujic*, Peiguo Yang, Claudio Macias-Trevino, Aysu N Uygur, Francesco S Loffredo, James R Pancoast, Miook Cho, Jill Goldstein, Rachel M Tandias, Emilia Gonzalez, Ryan G Walker, Thomas B Thompson, Amy J Wagers, Yick W Fong, Richard T Lee. Circulating Growth Differentiation Factor 11/8 Levels Decline with Age. Circ. Res 2015; 7442: 467-73. (*co-first author)

29. Long Lin, Peiguo Yang, Xinxin Huang, Qun Lu, Hui Zhang, Hong Zhang. The scaffold protein EPG-7 links cargo/receptor complexes with the autophagic assembly machinery. J Cell Biol 2013; 201:113-129.

30. Qianqian Liang, Peiguo Yang, E Tian, Jinghua Han, Hong Zhang. The C. elegans ATG101 homolog EPG-9 directly interacts with EPG-1/Atg13 and is essential for autophagy. Autophagy 2012; 8:1426-33.

31. Qun Lu, Peiguo Yang, Xinxin Huang, Wanqiu Hu, Bin Guo, Fan Wu, Long Lin, Attila L. Kovács, Li Yu, Hong Zhang. The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes. Dev Cell 2011; 21:343-357.

32. Ye Tian, Haiyan Ren, Yu Zhao, Qun Lu, Xinxin Huang, Peiguo Yang, Hong Zhang. Four metazoan autophagy genes regulate cargo recognition, autophagosome formation and autolysosomal degradation. Autophagy 2010; 6:984-5.

33. Ye Tian*, Zhipeng Li*, Wanqiu Hu*, Haiyan Ren*, E Tian, Yu Zhao, Qun Lu, Xinxin Huang, Peiguo Yang, Xin Li, Xiaochen Wang, Attila L. Kova ́cs, Li Yu, Hong Zhang. C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms. Cell 2010; 141:1042-55.