NEWS & EVENTS Event Calendars Event

Time & Date

4:00-5:30 PM, Friday, Oct 30, 2020

Venue

Lecture Hall, 1F, Building 5, Yunqi Campus

Host

Hongtao Yu, Chair Professor and Dean of School of Life Sciences, Westlake University

Audience

Faculty and Staff,Graduate Students,Undergraduate Students

Category

Academics and Research

84th Westlake Master Forum | Feng Shao: Pyroptosis, Inflammation and Antitumor Immunity

Time:4:00-5:30 PM, Friday, Oct 30, 2020

Venue: Lecture Hall, 1F, Building 5, Yunqi Campus

Host: Hongtao Yu, Chair Professor and Dean of School of Life Sciences, Westlake University



Speaker: Prof. Feng Shao, Academician of Chinese Academy of Sciences, Investigator and Deputy Director for Academic Affairs, NIBS, Beijing, China


Dr. Feng Shao’s laboratory is interested in studying molecular mechanisms of bacterial infection and host innate immunity defense. Bacterial pathogens use specialized secretion systems such as type III/IV secretion system to inject effector proteins into host cells, serving as a key and universal virulence mechanism. The effectors usually harbor a unique and potent activity that modulates the function of key signaling molecules in the host, and this plays a critical role in bacterial survival and systemic infections. Using pathogens such as Shigella, Salmonella, Enteropathogenic E. coli (EPEC), Legionella and Burkholderia as the model, we are working to discover and reveal some novel and common biochemical mechanisms utilized by bacterial effectors in modulating host signal transduction pathways. However, little is known about how the inflammasome is assembled/activated, and the signaling cascade upstream of the inflammasome remains obscure. They are combining multiple approaches including biochemical reconstitution, cell biology and mouse genetics to identify new components in pathogen-induced inflammasome activation and to further reveal the underlying biochemical mechanism.



Title:

Pyroptosis, inflammation and antitumor immunity


Contact:

biguanying@westlake.edu.cn







Time & Date

4:00-5:30 PM, Friday, Oct 30, 2020

Venue

Lecture Hall, 1F, Building 5, Yunqi Campus

Host

Hongtao Yu, Chair Professor and Dean of School of Life Sciences, Westlake University

Audience

Faculty and Staff,Graduate Students,Undergraduate Students

Category

Academics and Research