ABOUT

Vaccine design and the analysis of immune responses are critical for global health security. Understanding the contribution of activating the innate immune system and the role of adaptive memory, both of systemic and tissue resident cells, is essential for optimizing the immunogenicity and efficacy of vaccines. Mastering knowledge of how these different domains of the immune system interact, will enable rapid development of next-generation platforms, such as mRNA and mucosal vaccines in response to evolving and emerging pathogens. Ultimately, integrating precise design with comprehensive immune profiling will accelerate the creation of universal vaccines, offering robust defenses against emerging pandemics and enduring threats to humanity.

This symposium explores advanced vaccine strategies targeting respiratory pathogens like SARS-CoV-2, Ebola, and influenza. The experts will discuss leveraging effector and resident memory B cells, antibody-mediated regulation of germinal centers, and conserved neuraminidase epitopes for universal vaccine design. By integrating systemic and local immune responses, these approaches aim to reduce morbidity, mortality, and viral spread, offering promising next-generation solutions against evolving viral threats through rational, mechanism-driven immunogen design.