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Westlake Multidisciplinary Research Initiative Center
Conducting original research that may have significant impacts to the community is one of the missions of Westlake University. A new Center, the Multidisciplinary Research Initiative Center (MRIC), is formed to further fulfill this mission. MRIC is set up to facilitate the collaboration of the PIs from different disciplines and encourage PIs to take high-risk, high-reward original scientific research. We anticipate this center will become the innovative powerhouse of Westlake University, fostering innovative research ideas that may ultimately benefit the whole society.
Westlake MRIC is calling for proposals from Westlake University principal investigators (PIs) four times a year (in January, April, July and October). Each PI can only participate in one team and submit one proposal. Each project could have two or three PIs from different disciplines.
Westlake MRIC will be led by Prof. Yang Yang, Dean of the School of Engineering, and supported by Vice President Prof. Min Qiu.
Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province
The Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province was established with approval by the Science Technology Department of Zhejiang Province, the Zhejiang Provincial Development and Reform Commission and the Zhejiang Provincial Department of Finance, on November 2019. Li Deng, Xu Yiming Endowed Chair Professor and Executive Dean of School of Science at Westlake University, will be the director of the Key Laboratory. The academic committee consists of prominent educators and scholars from China and overseas, providing advise on major issues in decision making process such as the strategic planning of the Key Laboratory.
Focusing on the development of new synthetic methodology and innovative synthetic strategies, the Key Laboratory aims to achieve rapid construction of libraries of bioactive functional molecules and efficient synthesis of novel functional materials, thereby providing materials for the original discovery and development of novel functional molecules of medicinal and biomedical applications. By achieving these goals, the Key Laboratory will become a world-class center of excellence in fundamental research and education.
Key Laboratory of Growth Regulation and Transformation Research of Zhejiang Province
Zhejiang provincial key laboratory for growth regulation and transformation research was established in November 2019 with the approval of Zhejiang provincial department of science and technology, Zhejiang provincial development and reform commission, and Zhejiang provincial department of finance. The laboratory will integrate its multidisciplinary strengths and strive to lead the genetic and translational medicine research related to tissue organ growth regulation, relying on the high throughput screening platform, mass spectrometry platform and animal center, etc. The members of the academic committee are famous experts and scholars in related fields.
Research purposes and contents:
Research work will revolve around "biological size, function, manipulation and disease", relying on our previous research of the organ growth control, the basis of the work in genetics, cell biology, biochemistry, physical methods and combined with artificial intelligence, clinical medicine, neuropsychology, pharmaceutical chemistry to carry out the basic theory and transformation application research. The specific research includes the following three purposes: 1. The role and mechanism of growth regulation in drosophila melanogasters; 2. Biological functions and mechanisms of mammalian organ size and growth; 3. Research and development of disease diagnosis and treatment through organ size regulation mechanism.
Zhejiang 3D Micro-Nano Processing and Characterization Studies
Zhejiang 3D Micro-Nano Processing and Characterization Studies Key Lab is established in February 2019 under the official approval from the Science and Technology Agency of Zhejiang Province. The lab marks one of the first batch of essential labs in Westlake University. The lab brings cohort resources from the school-level research platform for advanced micro-nano processing and testing in the School of Engineering and the university-wide research platform, the Westlake Center for Micro/Nano Fabrication. The existing facilities are hosted by the No.2 Building in Yunqi Campus with an overall floor area of 3,000 square meters and a total value of 60 million CNY.
The interdisciplinary-minded lab sets its key missions on the innovative research and application of 3D micro-nano processing and characterization technology based on the existing surface processing processes enabled micro-nano structures and components, coupled with its vision to create the futuristic synergy of the microelectronics integration technology and the micro-nano processing.
Zhejiang Structural Biology
The research in the Key Laboratory of Structural Biology of Zhejiang Province is focusing on biomacromolecular machines and membrane proteins related to important biological processes or human diseases. We are working to understand the assembly and regulation of biomacromolecular machines and the structure-function relationship of membrane proteins, and to explore their posttranslational modification and protein-protein interaction patterns under physiological and pathological conditions. Based on these studies, we are carrying out studies such as molecular dynamics simulation, protein design, small molecule tool design and drug development, with the aim of understanding the molecular mechanisms underlying the initiation and progression of human diseases and speeding up the development of effective treatments.